BMS-986205 新热促

参考资料仅供科学研究，不可用于个人用途。

货号：BCP20339CAS号：1923833-60-6纯度：98%

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CAS号	1923833-60-6	货号	BCP20339
中文名	BMS-986205
英文名	BMS986205
中文别名
英文别名	BMS986205;BMS 986205; ONO-7701; ONO 7701; ONO7701; F-001287; F001287; F001287; Linrodostat;
SMILES	CC(C1CCC(CC1)C2=C3C=C(C=CC3=NC=C2)F)C(=O)NC4=CC=C(C=C4)Cl
化学名称
分子式	C24H24ClFN2O	分子量	410.91
纯度	98%	配送	惯例下常温包邮
产品描述	BMS-986205 is a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. BMS-986205 specifically targets and binds to IDO1, a cytosolic enzyme responsible for the oxidation of the amino acid tryptophan into the immunosuppressive metabolite kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, and T lymphocytes, and causes a reduction in tumor-associated regulatory T cells (Tregs).

BMS-986205 新 热 促