参考资料
在线咨询
购买咨询即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS号 | 1134822-09-5 | 货号 | BCP19043 |
| 中文名 | Ivacaftor benzenesulfonate | ||
| 英文名 | Ivacaftor benzenesulfonate | ||
| 中文别名 | |||
| 英文别名 | VX-770 benzenesulfonate;VX770 benzenesulfonate;VX 770 benzenesulfonate; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C30H34N2O6S | 分子量 | 550.67 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | in vitro: In recombinant cells VX-770 increased CFTR channel open probability (P(o)) in both the F508del processing mutation and the G551D gating mutation. VX-770 also increased Cl(-) secretion in cultured human CF bronchial epithelia (HBE) carrying the G551D gating mutation on one allele and the F508del processing mutation on the other allele by approximately 10-fold, to approximately 50% of that observed in HBE isolated from individuals without CF . in vivo: At day 28, in the group of subjects who received 150 mg of VX-770, the median change in the nasal potential difference (in response to the administration of a chloride-free isoproterenol solution) from baseline was -3.5 mV (range, -8.3 to 0.5; P=0.02 for the within-subject comparison, P=0.13 vs. placebo), and the median change in the level of sweat chloride was -59.5 mmol per liter (range, -66.0 to -19.0; P=0.008 within-subject, P=0.02 vs. placebo) . Toxicity: Six severe adverse events occurred in two subjects (diffuse macular ra | ||
在购买和使用瀚香生物产品的过程中，您遇到的任何问题，都可以咨询我们的免费热线：400-099-8200，或者和我们的客服 
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
Tags:Ivacaftor benzenesulfonate 供应商,Ivacaftor benzenesulfonate 购买,Ivacaftor benzenesulfonate 生产,Ivacaftor benzenesulfonate 批量,Ivacaftor benzenesulfonate 供应,Ivacaftor benzenesulfonate 订购,Ivacaftor benzenesulfonate 采购