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Ivacaftor 结构式

依伐卡托

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP01857CAS号 :873054-44-5纯度:98%
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  • 基本信息与产品描述
CAS号 873054-44-5 货号 BCP01857
中文名 依伐卡托
英文名 Ivacaftor
中文别名 依法卡托;艾伐卡托;
英文别名 VX-770;VX770;VX 770;Kalydeco;
SMILES O=C(C1=CNC2=C(C=CC=C2)C1=O)NC3=CC(O)=C(C(C)(C)C)C=C3C(C)(C)C
化学名称
分子式 C24H28N2O3 分子量 392.49
纯度 98% 配送 惯例下常温包邮
产品描述 Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.
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