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CAS号 | 1654725-02-6 | 货号 | BCP23611 |
中文名 | GLPG1837 | ||
英文名 | GLPG1837 | ||
中文别名 | |||
英文别名 | GLPG 1837; GLPG1837; ABBV-974; ABBV 974; ABBV974; | ||
SMILES | |||
化学名称 | |||
分子式 | C16H20N4O3S | 分子量 | 348.42 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | GLPG-1837, also known as ABBV-974, is a novel cystic fibrosis transmembrane conductance regulator (CFTR) potentiator1. GLPG1837 was generally safe and well tolerated in healthy subjects up to the highest dose of 800 mg twice daily for 2 weeks. GLPG1837 shows enhanced efficacy on CFTR mutants harboring Class III mutations compared to Ivacaftor, the first marketed potentiator. |
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