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CAS号 | 1202055-34-2 | 货号 | BCP28300 |
中文名 | NMS-P715 analog | ||
英文名 | NMS-P715 analog | ||
中文别名 | |||
英文别名 | NMSP-715; NMSP715; NMSP 715; | ||
SMILES | |||
化学名称 | |||
分子式 | C35H42N8O3 | 分子量 | 622.76 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | NMS-P715 is a selective and orally bioavailable MPS1 inhibitor, which selectively reduces cancer cell proliferation, leaving normal cells almost unaffected. NMS-P715 accelerates mitosis and affects kinetochore components localization causing massive aneuploidy and cell death in a variety of tumoral cell lines and inhibits tumor growth in preclinical cancer models. Inhibiting the SAC could represent a promising new approach to selectively target cancer cells. |
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