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CAS号 | 121080-63-5 | 货号 | BCP24172 |
中文名 | SN-38葡糖苷酸 | ||
英文名 | SN-38 Glucuronide | ||
中文别名 | |||
英文别名 | SN38 glucuronide;SN 38 glucuronide;SN-38G; | ||
SMILES | CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC6C(C(C(C(O6)C(=O)O)O)O)O | ||
化学名称 | |||
分子式 | C28H28N2O11 | 分子量 | 568.53 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SN38 glucuronide is a metabolite of irinotecan. Irinotecan is a drug used for the treatment of cancer. Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. In chemical terms, it is a semisynthetic analogue of the natural alkaloid camptothecin. Its main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. Irinotecan received accelerated approval by the U. S. |
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