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CAS号 | 1391107-89-3 | 货号 | BCP31671 |
中文名 | BM-1197 | ||
英文名 | BM-1197 | ||
中文别名 | |||
英文别名 | BM1197;BM 1197; | ||
SMILES | |||
化学名称 | |||
分子式 | C53H59ClF4N6O7S4 | 分子量 | 1131.77 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BM-1197 is a potent, specific dual inhibitor of Bcl-2 and Bcl-xL with Ki of <1 nM, shows >1,000-fold selectivity over Mcl-1; exerts potent growth-inhibitory activity in 7 of 12 small cell lung cancer cell lines tested and induces mechanism-based apoptotic cell death, induces complete and long-lasting tumor regression in vivo. |
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