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Revaprazan Hydrochloride 结构式

盐酸瑞伐拉赞

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP09645CAS号 :178307-42-1纯度:98%
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  • 基本信息与产品描述
CAS号 178307-42-1 货号 BCP09645
中文名 盐酸瑞伐拉赞
英文名 Revaprazan Hydrochloride
中文别名 盐酸洛氟普啶;
英文别名 Revaprazan HCl;SB 641257 Hydrochloride;SB 641257A; YH 1885; YH-1885; YH1885;
SMILES
化学名称
分子式 C22H24ClFN4 分子量 398.9
纯度 98% 配送 惯例下常温包邮
产品描述 Revaprazan Hydrochloride is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Revaprazan concentrates highly in the gastric parietal cell canaliculus and on entering this acidic environment is instantly protonated and binds competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.
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