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| CAS号 | 2165322-95-0 | 货号 | BCP31313 |
| 中文名 | USP25 and 28 inhibitor AZ-2 | ||
| 英文名 | USP25 and 28 inhibitor AZ-2 | ||
| 中文别名 | 2-((5-bromo-2-((3-(trifluoromethoxy)benzyl)oxy)benzyl)amino)ethan-1-ol; | ||
| 英文别名 | USP25/28 inhibitor AZ2；AZ2；AZ-2；AZ 2; | ||
| SMILES | C1=CC(=CC(=C1)OC(F)(F)F)COC2=C(C=C(C=C2)Br)CNCCO | ||
| 化学名称 | |||
| 分子式 | C17H17BrF3NO3 | 分子量 | 420.23 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | USP25 and 28 inhibitor AZ-2 is a potent, selective, dual USP25/28 inhibitor with IC50 of 0.9/0.9 uM, respectively; shows a high degree of selectivity over other deubiquitinases (USP4,7 etc.); demonstrates target engagement against both USP25 and USP28 in cells, elicits modulation of both the total levels and the half-life of the c-Myc oncoprotein in cells, and also induces apoptosis and inhibits cell viability in a range of cancer cell lines. | ||
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