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| CAS号 | 919091-63-7 | 货号 | BCP48946 |
| 中文名 | RA-9 | ||
| 英文名 | RA-9 | ||
| 中文别名 | |||
| 英文别名 | RA 9; RA9; RA-9 UPS inhibitor; | ||
| SMILES | C1C(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])CN1 | ||
| 化学名称 | |||
| 分子式 | C19H15N3O5 | 分子量 | 365.34 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | RA-9 is a potent and selective proteasome-associated deubiquitinating enzymes (DUBs) inhibitor with favorable toxicity profile and anticancer activity. RA-9 blocks ubiquitin-dependent protein degradation without impacting 20S proteasome proteolytic activity. RA-9 selectively induces onset of apoptosis in ovarian cancer cell lines and primary cultures derived from donors. RA-9 induces endoplasmic reticulum (ER)-stress responses in ovarian cancer cells. | ||
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