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Golotimod 结构式

Golotimod

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP24651CAS号 :229305-39-9纯度:98%
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  • 基本信息与产品描述
CAS号 229305-39-9 货号 BCP24651
中文名 Golotimod
英文名 Golotimod
中文别名 gamma-D-谷氨酰-L-色氨酸;
英文别名 H-D-Glu(L-Trp-OH)-OH;SCV 07;gamma-D-Glu-L-trp;SCV-07;SCV07;
SMILES O=C(CC[C@@](N)(C(O)=O)[H])N[C@]([H])(C(O)=O)CC1=CNC2=C1C=CC=C2
化学名称
分子式 C16H19N3O5 分子量 333.34
纯度 98% 配送 惯例下常温包邮
产品描述 Golotimod is an orally bioavailable synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities. Although the exact mechanism of action is unknown, golotimod appears to inhibit the expression of STAT-3, reversing immunosuppression and stimulating an anti-tumor immune response. This agent may stimulate the production of T-lymphocytes, in particular the helper T (Th1) cells, activate macrophages, and increase levels of interleukin 2 and interferon gamma. STAT-3, a transcription factor upregulated in many cancer cell types, is involved in tumor cell growth and survival and immunosuppression.
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