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| CAS号 | 2309409-79-6 | 货号 | BCP49698 |
| 中文名 | CMP-5双盐酸盐 | ||
| 英文名 | CMP-5 dihydrochloride | ||
| 中文别名 | CMP-5二盐酸盐; | ||
| 英文别名 | CMP-5 2HCl; | ||
| SMILES | CCN1C2=C(C=C(C=C2)CNCC3=CC=CC=N3)C4=CC=CC=C41.Cl.Cl | ||
| 化学名称 | |||
| 分子式 | C21H23Cl2N3 | 分子量 | 388.3 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | CMP-5 hydrochloride is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 hydrochloride selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 hydrochloride prevents EBV-driven B-lymphocyte transformation but leaving normal B cells unaffected. | ||
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