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Quinacrine dihydrochloride 结构式

喹吖因二盐酸

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货号 :BCP49707CAS号 :69-05-6纯度:98%
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  • 基本信息与产品描述
CAS号 69-05-6 货号 BCP49707
中文名 喹吖因二盐酸
英文名 Quinacrine dihydrochloride
中文别名 二盐酸奎吖因 ;阿的平 二盐酸盐;二盐酸阿的平;
英文别名 Quinacrine 2HCl;Mepacrine dihydrochloride; SN-390 dihydrochloride;
SMILES CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC.Cl.Cl
化学名称
分子式 C23H32Cl3N3O 分子量 472.88
纯度 98% 配送 惯例下常温包邮
产品描述 Quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. Quinacrine may inhibit the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB), which may result in the induction of tumor suppressor p53 transcription, the restoration of p53-dependent apoptotic pathways, and tumor cell apoptosis. Continuous NF-kappaB signaling, present in many tumors and in chronic inflammatory processes, promotes the expression of antiapoptotic proteins and cytokines while downregulating the expression of proapoptotic proteins, such as p53.
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