参考资料
在线咨询
购买咨询即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS号 | 2563855-03-6 | 货号 | BCP44951 |
| 中文名 | K-975 | ||
| 英文名 | K-975 | ||
| 中文别名 | |||
| 英文别名 | K975; K 975; | ||
| SMILES | CC1=C(C=C(C=C1)NC(=O)C=C)OC2=CC=C(C=C2)Cl | ||
| 化学名称 | |||
| 分子式 | C16H14ClNO2 | 分子量 | 287.74 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | K-975 is a first-in-class TEAD inhibitor, directly inhibiting YAP/TAZ-TEAD protein-protein interaction and showing a potent anti-tumor effect in malignant pleural mesothelioma. K-975 was covalently bound to an internal cysteine residue located in the palmitate-binding pocket of TEAD. K-975 had a strong inhibitory effect against protein-protein interactions between YAP1/TAZ and TEAD in cell-free and cell-based assays. Furthermore, K-975 potently inhibited the proliferation of NF2-non-expressing MPM cell lines compared with NF2-expressing MPM cell lines. K-975 also suppressed tumor growth and provided significant survival benefit in MPM xenograft models. | ||
在购买和使用瀚香生物产品的过程中，您遇到的任何问题，都可以咨询我们的免费热线：400-099-8200，或者和我们的客服 
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。相关产品推荐
查看更多 >
Tags:K-975 供应商,K-975 购买,K-975 生产,K-975 批量,K-975 供应,K-975 订购,K-975 采购