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| CAS号 | 2749555-66-4 | 货号 | BCP46463 |
| 中文名 | DX3-213B | ||
| 英文名 | DX3-213B | ||
| 中文别名 | |||
| 英文别名 | DX3213B; DX3 213B; | ||
| SMILES | CC(C)S(=O)(=O)C1=CC=C(C=C1)S(=O)(=O)N2CCCC(C2)C(=O)N3CCC(CC3)(F)F | ||
| 化学名称 | |||
| 分子式 | C20H28F2N2O5S2 | 分子量 | 478.57 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | DX3-213B is a potent Oxidative Phosphorylation Inhibitor (MIA PaCa-2 GI50 = 11 nM) for the Treatment of Pancreatic Cancer. DX3-213B disrupts adenosine triphosphate (ATP) generation, inhibits complex I function, and results in the growth inhibition of pancreatic cancer cells in the low nanomolar range. Importantly, the oral administration of DX3-213B resulted in significant in vivo efficacy in a pancreatic cancer syngeneic model without obvious toxicity. | ||
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