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CAS号 | 294623-49-7 | 货号 | BCP28510 |
中文名 | L006235 | ||
英文名 | L006235 | ||
中文别名 | |||
英文别名 | L 006235; L-006235; L235; L-235; L 235; | ||
SMILES | CN1CCN(CC1)C2=NC(=CS2)C3=CC=C(C=C3)C(=O)NC4(CCCCC4)C(=O)NCC#N | ||
化学名称 | |||
分子式 | C24H30N6O2S | 分子量 | 466.6 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | L-006235 is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC50 of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K (Ki=0.2 nM) over cathepsin B, cathepsin L, and cathepsin S (Ki=1, 6, and 47 μM, respectively). L-006235 can reduce collagen degradation and prevent bone loss. |
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