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CAS号 | 831234-13-0 | 货号 | BCP37804 |
中文名 | AC1903 | ||
英文名 | AC1903 | ||
中文别名 | |||
英文别名 | AC 1903; AC-1903; | ||
SMILES | C1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2NCC4=CC=CO4 | ||
化学名称 | |||
分子式 | C19H17N3O | 分子量 | 303.36 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | AC1903 is a specific and selective inhibitor of TRPC5 and has podocyte-protective properties. AC1903 does no effects on TRPC4 or TRPC6 currents and shows no off-target effects in kinase profiling assays. AC1903 suppresses severe proteinuria and prevents podocyte loss in focal segmental glomerulosclerosis (FSGS) rat model. |
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