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CAS号 | 926023-82-7 | 货号 | BCP24615 |
中文名 | AMTB hydrochloride | ||
英文名 | AMTB hydrochloride | ||
中文别名 | |||
英文别名 | AMTB HCl; | ||
SMILES | CC1=CC(=CC=C1)COC2=CC=CC=C2C(=O)N(CCCN)CC3=CC=CS3.Cl | ||
化学名称 | |||
分子式 | C23H26N2O2S.HCl | 分子量 | 431.0 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | AMTB is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. For rats, AMTB (10 mg/kg) significantly attenuated reflex responses to noxious urinary bladder distension (UBD) to 5.42 and 56.51% of the maximal visceromotor reflex (VMR) response and pressor response, respectively. The ID50 value on VMR response was 2.42 +/- 0.46 mg/kg. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive reflex responses in the rat. |
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