优立替尼促

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货号：BCP04232CAS号：869886-67-9纯度：98%

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CAS号	869886-67-9	货号	BCP04232
中文名	优立替尼
英文名	Ulixertinib
中文别名
英文别名	1956366-10-1; BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271;;
SMILES	O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO
化学名称
分子式	C21H22Cl2N4O2	分子量	433.33
纯度	98%	配送	惯例下常温包邮
产品描述	Ulixertinib, also known as BVD-523 and VRT752271, is an inhibitors of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.

优立替尼 促