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RO5126766 结构式

RO5126766

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP21067CAS号 :946128-88-7纯度:98%
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  • 基本信息与产品描述
CAS号 946128-88-7 货号 BCP21067
中文名 RO5126766
英文名 RO5126766
中文别名
英文别名 RO 5126766; RO5126766; CH5126766; CH5126766; CH 5126766;
SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F
化学名称
分子式 C21H18FN5O5S 分子量 471.46
纯度 98% 配送 惯例下常温包邮
产品描述 RO5126766, also known as CH5126766, is a protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity. Raf/MEK dual kinase Inhibitor RO5126766 specifically inhibits the kinase activities of Raf and MEK, resulting in the inhibition of of target gene transcription that promotes malignant transformation of cells. Both Raf and MEK are serine/threonine-specific kinases that respond to extracellular stimuli, such as mitogens, and are involved in the regulation of cellular processes, such as gene expression, mitosis, differentiation, and apoptosis.
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