硫酸氯吡格雷新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP06463CAS号：120202-66-6纯度：98%

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CAS号	120202-66-6	货号	BCP06463
中文名	硫酸氯吡格雷
英文名	Clopidogrel hydrogen sulfate
中文别名
英文别名	Clopidogrel sulfate;(S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate;
SMILES
化学名称
分子式	C16H18ClNO6S2	分子量	419.89
纯度	98%	配送	惯例下常温包邮
产品描述	Clopidogrel is an effective antiplatelet agent useful for the treatment of ischemic cerebrovascular, cardiac, and peripheral arterial disease. Clopidogrel abolishes the inhibitory P2Y(AC) receptor-mediated ADP effects on prostaglandin E(1)-stimulated, cAMP-dependent phosphorylation of VASP without affecting epinephrine, thrombin, and thromboxane signaling. VASP phosphorylation is known to be closely correlated with the inhibition of platelet and fibrinogen receptor (glycoprotein IIb/IIIa) activation. Therefore, inhibition of the platelet P2Y(AC) ADP receptor and its intracellular signaling, including decreased VASP phosphorylation, is suggested as a molecular mechanism of clopidogrel action. Clopidogrel ingestion reduced the thrombus volume significantly (p < 0.05) at 100 and 2600 s-1 (39 and 51% respectively). clopidogrel reduced significantly the fibrinopeptide A plasma levels and the fibrin deposition at shear rates below 650 s-1 .

硫酸氯吡格雷 新