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CAS号 | 367514-87-2 | 货号 | BCP22902 |
中文名 | 鲁拉西酮 | ||
英文名 | Lurasidone | ||
中文别名 | |||
英文别名 | SM13496; SM-13496; SM 13496; SM13,496; SM-13,496; SM 13,496; | ||
SMILES | |||
化学名称 | |||
分子式 | C28H36N4O2S | 分子量 | 492.68 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Lurasidone is a new atypical antipsychotic. I is also approved for the treatment of depressive episodes associated with bipolar I disorder (bipolar depression) in adults when used alone or in combination with lithium or valproate. Lurasidone acts as an antagonist of the following sites: α1-adrenergic receptor (Ki = 48 nM); α2A-adrenergic receptor (Ki = 1.6 nM); α2C-adrenergic receptor (Ki = 10.8 nM); D1 receptor (Ki = 262 nM); D2 receptor (Ki = 1.7 nM); 5-HT2A receptor (Ki = 2.0 nM); 5-HT2C receptor (Ki = 415 nM); 5-HT7 receptor (Ki = 0.5 nM). And as a partial agonist of the following sites: 5-HT1A receptor (Ki = 6.8 nM). (Source: http://en.wikipedia.org/wiki/Lurasidone). |
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