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CAS号 | 150399-23-8 | 货号 | BCP23433 |
中文名 | 培美曲塞二钠 | ||
英文名 | Pemetrexed disodium | ||
中文别名 | |||
英文别名 | LY-231514 disodium;Alimta;LY 231514 disodium;LY231514 disodium; | ||
SMILES | |||
化学名称 | |||
分子式 | C20H19N5Na2O6 | 分子量 | 471.37 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Pemetrexed disodium is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. |
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