CFI-400945 fumarate

参考资料仅供科学研究，不可用于个人用途。

货号：BCP25931CAS号：1616420-30-4纯度：98%

在线咨询

购买咨询

全国免运费！免费咨询：400-099-8200 或手机联系：13472751340

* 必填项

请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。

* Required Fields.

Please complete the form below and we will contact you shortly.

* Required Fields.

Please complete the form below and we will contact you shortly.

CAS号	1616420-30-4	货号	BCP25931
中文名	CFI-400945 fumarate
英文名	CFI-400945 fumarate
中文别名
英文别名	Ocifisertib Fumarate;CFI400945; CFI 400945; CFI-400945；CFI400945 fumarate;
SMILES	CC1CN(CC(O1)C)CC2=CC=C(C=C2)C=CC3=NNC4=C3C=CC(=C4)C5CC56C7=C(C=CC(=C7)OC)NC6=O.C(=CC(=O)O)C(=O)O
化学名称
分子式	C37H38N4O7	分子量	650.72
纯度	98%	配送	惯例下常温包邮
产品描述	CFI-400945 fumarate is an orally available fumarate salt form of CFI-400945, a polo-like kinase 4 (PLK4) inhibitor with potential antineoplastic activity. Upon oral administration, polo-like kinase 4 inhibitor CFI-400945 selectively inhibits PLK4, which results in the disruption of mitosis and the induction of apoptosis. PLK4 inhibition also prevents cell division and inhibits proliferation of PLK4-overexpressing tumor cells. PLK4, a member of the polo family of serine/threonine kinases overexpressed in a variety of cancer cell types, plays a crucial role in the regulation of centriole duplication during the cell cycle.