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CAS号 | 1883711-97-4 | 货号 | BCP32591 |
中文名 | AM-0902 | ||
英文名 | AM-0902 | ||
中文别名 | |||
英文别名 | AM 0902; AM0902; | ||
SMILES | CN1C=NC2=C1C(=O)N(C=N2)CC3=NC(=NO3)CCC4=CC=C(C=C4)Cl | ||
化学名称 | |||
分子式 | C17H15ClN6O2 | 分子量 | 370.8 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | AM-0902 is a potent and selective Transient Receptor Potential A1 (TRPA1) Antagonist Demonstrating Potent in Vivo Activity with pharmacokinetic properties allowing for >30-fold coverage of the rat TRPA1 IC50 in vivo. AM-0902 showed rTRPA1 45Ca2+ Flux IC50=0.071 microM and hTRPA1 45Ca2+ Flux IC50=0.131 microM. AM-0902 demonstrated dose-dependent inhibition of AITC-induced flinching in rats, validating its utility as a tool for interrogating the role of TRPA1 in in vivo pain models. |
Tags:AM-0902 供应商,AM-0902 购买,AM-0902 生产,AM-0902 批量,AM-0902 供应,AM-0902 订购,AM-0902 采购