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γ-Secretase Inhibitor XXI 结构式

γ-Secretase Inhibitor XXI

参考资料 仅供科学研究，不可用于个人用途。
货号 ：BCP02178CAS号 ：209986-17-4纯度：98%
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  • 基本信息与产品描述
CAS号 209986-17-4 货号 BCP02178
中文名 γ-Secretase Inhibitor XXI
英文名 γ-Secretase Inhibitor XXI
中文别名
英文别名 Compound E;DuPont E;g-Secretase Inhibitor XXI;gamma-Secretase Inhibitor XXI;
SMILES CC(C(=O)NC1C(=O)N(C2=CC=CC=C2C(=N1)C3=CC=CC=C3)C)NC(=O)CC4=CC(=CC(=C4)F)F
化学名称
分子式 C27H24F2N4O3 分子量 490.5
纯度 98% 配送 惯例下常温包邮
产品描述 Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM).
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