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| CAS号 | 1146699-66-2 | 货号 | BCP01770 |
| 中文名 | 塞来西布 | ||
| 英文名 | Avagacestat | ||
| 中文别名 | |||
| 英文别名 | BMS-708163;BMS708163;BMS 708163; | ||
| SMILES | O=C(N)[C@H](N(CC1=CC=C(C2=NOC=N2)C=C1F)S(=O)(C3=CC=C(Cl)C=C3)=O)CCC(F)(F)F | ||
| 化学名称 | |||
| 分子式 | C20H17ClF4N4O4S | 分子量 | 520.89 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Avagacestat, also known as BMS-708163, is an oral GSI designed for selective inhibition of Aβ synthesis currently in development for the treatment of mild to moderate and predementia AD. In addition to the desired effect on Aβ synthesis, GSIs affect Notch processing, which is thought to mediate some toxic adverse effects reported with this drug class. | ||
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