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| CAS号 | 2114339-57-8 | 货号 | BCP38455 |
| 中文名 | Amcenestrant | ||
| 英文名 | Amcenestrant | ||
| 中文别名 | |||
| 英文别名 | SAR439859; SAR-439859; SAR 439859; | ||
| SMILES | C1CC2=C(C=CC(=C2)C(=O)O)C(=C(C1)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)OC5CCN(C5)CCCF | ||
| 化学名称 | |||
| 分子式 | C31H30Cl2FNO3 | 分子量 | 554.48 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Amcenestrant, also known as SAR439859, is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells | ||
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