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CAS号 | 2407529-33-1 | 货号 | BCP43932 |
关联产品 | 1953133-47-5(Giredestrant) | ||
中文名 | Giredestrant tartrate | ||
英文名 | Giredestrant tartrate | ||
中文别名 | |||
英文别名 | GDC-9545 tartrate; GDC9545; GDC 9545; RG6171; RG-6171; RG 6171; | ||
SMILES | CC1CC2=C(C(N1CC(CO)(F)F)C3=C(C=C(C=C3F)NC4CN(C4)CCCF)F)NC5=CC=CC=C25.C(C(C(=O)O)O)(C(=O)O)O | ||
化学名称 | |||
分子式 | C31H37F5N4O7 | 分子量 | 672.6 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. |
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