MRTX849 新
参考资料
仅供科学研究,不可用于个人用途。
规格 | 价格(CNY) | 是否现货 | 购买咨询 |
---|---|---|---|
500.00 mg | ¥2500.00 | In-stock | 购买咨询 |
1.00 g | ¥3800.00 | In-stock | 购买咨询 |
2.00 g | ¥6500.00 | In-stock | 购买咨询 |
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CAS号 | 2326521-71-3 | 货号 | BCP31538 |
关联产品 | 2490716-96-4(MRTX849 analog 24) 2561529-96-0(MRTX849-溴丙酸衍生物) | ||
中文名 | MRTX849 | ||
英文名 | MRTX849 | ||
中文别名 | |||
英文别名 | MRTX-849; MRTX 849; | ||
SMILES | N#CC[C@@H]1N(C(C(F)=C)=O)CCN(C2=C3C(CN(C4=C5C(Cl)=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)C1 | ||
化学名称 | |||
分子式 | C32H35ClFN7O2 | 分子量 | 604.13 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | MRTX849 is a potent, highly selective, oral available KRAS G12C inhibitor. MRTX849 maximizes inhibition by irreversibly locking the KRAS molecule in its inactive state, thereby preventing tumor cell growth which results in tumor cell death. MRTX849 exhibited significantly improved half-life and penetration into the tumor, shutting down KRAS signaling for the entire dosing interval, and showing a higher degree of antitumor activity than previous KRAS mutant-selective inhibitors. |
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