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CAS号 | 2561529-96-0 | 货号 | BCP44575 |
关联产品 | 2490716-96-4(MRTX849 analog 24) 2326521-71-3(MRTX849 ) | ||
中文名 | MRTX849-溴丙酸衍生物 | ||
英文名 | MRTX849 acid | ||
中文别名 | |||
英文别名 | |||
SMILES | C=C(C(=O)N1CCN(CC1CC#N)C2=NC(=NC3=C2CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)OCC6CCCN6CCC(=O)O)F | ||
化学名称 | |||
分子式 | C34H37ClFN7O4 | 分子量 | 662.15 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2. LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50s between 0.25 and 0.76 μM). |
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