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| CAS号 | 2765082-12-8 | 货号 | BCP49669 |
| 中文名 | 泛KRAS抑制剂 | ||
| 英文名 | RMC-7977 | ||
| 中文别名 | |||
| 英文别名 | RMC 7977;RMC7977; | ||
| SMILES | CCN1C2=C3C=C(C=C2)C4=CSC(=N4)CC(C(=O)N5CCCC(N5)C(=O)OCC(CC3=C1C6=C(N=CC(=C6)N7CCN(CC7)C8CC8)C(C)OC)(C)C)NC(=O)C9C1C9COC1 | ||
| 化学名称 | |||
| 分子式 | C47H60N8O6S | 分子量 | 865.1 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRASG12C cancer models. | ||
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