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Niclosamide 结构式

氯硝柳胺

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP22958CAS号 :50-65-7纯度:98%
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  • 基本信息与产品描述
CAS号 50-65-7 货号 BCP22958
中文名 氯硝柳胺
英文名 Niclosamide
中文别名
英文别名 Niclocide;BAY 2353; NSC 178296; WR 46234; BAY-2353; NSC-178296; WR-46234; BAY2353; NSC178296; WR46234;
SMILES C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
化学名称
分子式 C13H8Cl2N2O4 分子量 327.12
纯度 98% 配送 惯例下常温包邮
产品描述 Niclosamide is an oral antihelminthic drug, which has been used to treat tapeworm infection for about 50 years. Niclosamide is also used as a molluscicide for water treatment in schistosomiasis control programs. Recently, several groups have independently discovered that niclosamide is also active against cancer cells. Evidence supports that niclosamide targets multiple signaling pathways (NF-κB, Wnt/β-catenin, Notch, ROS, mTORC1, and Stat3), most of which are closely involved with cancer stem cells. Given its potential antitumor activity, clinical trials for niclosamide and its derivatives are warranted for cancer treatment.
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