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| CAS号 | 637774-61-9 | 货号 | BCP24033 |
| 中文名 | SR13668 | ||
| 英文名 | SR13668 | ||
| 中文别名 | |||
| 英文别名 | SR 13668; SR-13668; | ||
| SMILES | CCOC(=O)C1=CC2=C(C=C1)NC3=C(C4=C(C=C23)C5=C(N4)C=CC(=C5)C(=O)OCC)OC | ||
| 化学名称 | |||
| 分子式 | C25H22N2O5 | 分子量 | 430.45 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | SR13668 is an Akt inhibitor, is also a n orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic and antiangiogenic activities. Akt inhibitor SR13668 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation, and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. | ||
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