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Azvudine 结构式

阿兹夫定

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货号 :BCP34041CAS号 :1011529-10-4纯度:98%
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  • 基本信息与产品描述
CAS号 1011529-10-4 货号 BCP34041
中文名 阿兹夫定
英文名 Azvudine
中文别名
英文别名 RO-0622;RO 0622;RO0622;
SMILES C1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)F
化学名称
分子式 C9H11FN6O4 分子量 286.22
纯度 98% 配送 惯例下常温包邮
产品描述 Azvudine is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM). Azvudine inhibits NRTI-resistant viral strains[1]. Azvudine is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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