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CAS号 | 41575-94-4 | 货号 | BCP22717 |
中文名 | 卡铂 | ||
英文名 | Carboplatin | ||
中文别名 | |||
英文别名 | cis-Diammine(1,1-cyclobutanedicarboxylato)platinum; | ||
SMILES | O=C(O[Pt]O1)C2(CCC2)C1=O.N.N | ||
化学名称 | |||
分子式 | C6H12N2O4Pt | 分子量 | 371.25 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Carboplatin is a second-generation platinum compound with a broad spectrum of antineoplastic properties. Carboplatin contains a platinum atom complexed with two ammonia groups and a cyclobutane-dicarboxyl residue. This agent is activated intracellularly to form reactive platinum complexes that bind to nucleophilic groups such as GC-rich sites in DNA, thereby inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These carboplatin-induced DNA and protein effects result in apoptosis and cell growth inhibition. |
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