甘氨鹅脱氧胆酸新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP49686CAS号：640-79-9纯度：98%

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CAS号	640-79-9	货号	BCP49686
中文名	甘氨鹅脱氧胆酸
英文名	Glycochenodeoxycholic acid
中文别名	甘鹅去氧胆酸;甘氨鹅去氧胆酸;
英文别名	GCDC;Glycochenodeoxycholate;Chenodeoxycholylglycine;Glycine chenodeoxycholate;
SMILES	CC(CCC(=O)NCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
化学名称
分子式	C26H43NO5	分子量	449.62
纯度	98%	配送	惯例下常温包邮
产品描述	Glycochenodeoxycholic acid is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC).

甘氨鹅脱氧胆酸 新