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CAS号 | 66611-37-8 | 货号 | BCP24844 |
中文名 | BGP-15 dihydrochloride | ||
英文名 | BGP-15 dihydrochloride | ||
中文别名 | |||
英文别名 | BGP15; BGP-15; BGP 15;BGP-15 2HCl; | ||
SMILES | C CCN(CC1)CC(C | ||
化学名称 | |||
分子式 | C14H24Cl2N4O2 | 分子量 | 351.27 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BGP-15 is a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity. BGP-15 also inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury. Moreover, BGP-15 was found to prevent imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases. |
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