
PNU-282987 S enantiomer free base 新

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CAS号 | 737727-12-7 | 货号 | BCP25435 |
中文名 | PNU-282987 S enantiomer free base | ||
英文名 | PNU-282987 S enantiomer free base | ||
中文别名 | |||
英文别名 | |||
SMILES | C1CN2CCC1C(C2)NC(=O)C3=CC=C(C=C3)Cl | ||
化学名称 | |||
分子式 | C14H17ClN2O | 分子量 | 264.75 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). PNU-282987 is inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). |
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