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CAS号 | 198283-74-8 | 货号 | BCP25229 |
关联产品 | 209326-18-1(Tebanicline benzoate) 209326-19-2(Tebanicline dihydrochloride) 203564-54-9(Tebanicline HCl) 198283-73-7(Tebanicline) | ||
中文名 | Tebanicline tosylate | ||
英文名 | Tebanicline tosylate | ||
中文别名 | |||
英文别名 | ABT594 tosylate;Tebanicline tosilate; | ||
SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.C1CNC1COC2=CN=C(C=C2)Cl | ||
化学名称 | |||
分子式 | C16H19ClN2O4S | 分子量 | 370.85 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. |
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