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| CAS号 | 935273-79-3 | 货号 | BCP18385 |
| 中文名 | MK-4101 | ||
| 英文名 | MK-4101 | ||
| 中文别名 | |||
| 英文别名 | MK4101;MK 4101; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C24H24F5N5O | 分子量 | 493.47 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | MK-4101 is a potent and selective inhibitor of the Hedgehog Pathway. MK-401 Is Highly Active against Medulloblastoma and Basal Cell Carcinoma. MK-4101 showed anti-tumor activity through the inhibition of proliferation and induction of extensive apoptosis in tumor cells. MK-4101 was highly efficacious against primary medulloblastoma and BCC developing in the cerebellum and skin of Ptch1(+/-) mice. MK-4101 targets the Hh pathway in tumor cells, showing the maximum inhibitory effect on Gli1 MK-4101 also induced deregulation of cell cycle and block of DNA replication in tumors. | ||
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