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CAS号 | 956697-53-3 | 货号 | BCP02275 |
中文名 | 索尼吉布 | ||
英文名 | Erismodegib | ||
中文别名 | 索尼德吉; | ||
英文别名 | LDE225;LDE-225;NVP-LDE225;Sonidegib; NVP-LDE-225; NVP LDE225; | ||
SMILES | |||
化学名称 | |||
分子式 | C26H26F3N3O3 | 分子量 | 485.5 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Erismodegib selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway and, so, the inhibition of tumor cells in which this pathway is abnormally activated. |
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