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CC-115 结构式

CC-115

参考资料 仅供科学研究，不可用于个人用途。
货号 ：BCP16702CAS号 ：1228013-15-7纯度：98%
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  • 基本信息与产品描述
CAS号 1228013-15-7 货号 BCP16702
中文名 CC-115
英文名 CC-115
中文别名
英文别名 CC 115;CC115;
SMILES
化学名称
分子式 C16H16N8O 分子量 336.35
纯度 98% 配送 惯例下常温包邮
产品描述 CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC-115 binds to and inhibits the activity of DNA-PK and both raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK and TOR. DNA-PK, a serine/threonine kinase and a member of the PI3K-related kinase subfamily of protein kinases, is activated upon DNA damage and plays a key role in repairing double-stranded DNA breaks via the DNA nonhomologous end joining (NHEJ) pathway.
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