参考资料
在线咨询
购买咨询即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS号 | 1300118-55-1 | 货号 | BCP20709 |
| 中文名 | CC-115 (hydrochloride) | ||
| 英文名 | CC-115 (hydrochloride) | ||
| 中文别名 | |||
| 英文别名 | CC-115 (hydrochloride); | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C16H17ClN8O | 分子量 | 372.81 |
| 纯度 | 配送 | 惯例下常温包邮 | |
| 产品描述 | CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). IC50 value: 21 nM (for mTOR), 13 nM (for DNA-PK) Target: mTOR, DNA-PK in vitro: The IC50 values for CC-115 are >10 μM against a panel of CYP enzymes and >33 μM for the hERG ion channel. When screened in a single point assay at 10 μM against a Cerep receptor and enzyme panel only one target was inhibited >50% (PDE3, IC50 = 0.63 μM). in vivo: CC-115 shows good PK profiles across multiple species with 53%, 76%, and 100% oral bioavailability in mouse, rat, and dog, respectively. CC-115, with favorable physicochemical and pharmacokinetic properties, demonstrates mTOR pathway inhibition and tumor growth inhibition, as well as a good safety profile, suitable for clinical development. | ||
在购买和使用瀚香生物产品的过程中，您遇到的任何问题，都可以咨询我们的免费热线：400-099-8200，或者和我们的客服 
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。相关产品推荐
查看更多 >
Tags:CC-115 (hydrochloride) 供应商,CC-115 (hydrochloride) 购买,CC-115 (hydrochloride) 生产,CC-115 (hydrochloride) 批量,CC-115 (hydrochloride) 供应,CC-115 (hydrochloride) 订购,CC-115 (hydrochloride) 采购