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ND-630 结构式

ND-630

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货号 :BCP20893CAS号 :1434635-54-7纯度:98%
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  • 基本信息与产品描述
CAS号 1434635-54-7 货号 BCP20893
中文名 ND-630
英文名 ND-630
中文别名
英文别名 ND 630;ND630;NDI-010976; NDI 010976; NDI010976; GS-0976; GS0976; GS 0976;Firsocostat;
SMILES
化学名称
分子式 C28H31N3O8S 分子量 569.63
纯度 98% 配送 惯例下常温包邮
产品描述 ND-630, also known as GS-0976 and NDI-010976, is a potent ACC inhibitor. ND-630 nteracts within the ACC phosphopeptide acceptor and dimerization site to prevent dimerization and inhibit the enzymatic activity of both ACC isozymes, reduce fatty acid synthesis and stimulate fatty acid oxidation in cultured cells and in animals, and exhibit favorable drug-like properties. ND-630 reduces hepatic steatosis, improves insulin sensitivity, reduces weight gain without affecting food intake, and favorably affects dyslipidemia. When administered chronically to Zucker diabetic fatty rats, ND-630 reduces hepatic steatosis, improves glucose-stimulated insulin secretion, and reduces hemoglobin A1c (0.9% reduction).
  • 技术资料和支持
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