CP 640186 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP09761CAS号：591778-68-6纯度：98%

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CAS号	591778-68-6	货号	BCP09761
关联产品	591778-70-0（CP-640186 hydrochloride）
中文名	CP 640186
英文名	CP 640186
中文别名
英文别名	CP-640186;CP640186;
SMILES	C1CC(CN(C1)C2CCN(CC2)C(=O)C3=C4C=CC=CC4=CC5=CC=CC=C53)C(=O)N6CCOCC6
化学名称
分子式	C30H35N3O3	分子量	485.62
纯度	98%	配送	惯例下常温包邮
产品描述	CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. CP-640186 has recently been shown to be a potent inhibitor of isoforms of mammalian ACCs with IC50 values of about 55 nM. This is currently the only reported potent inhibitor of mammalian ACCs. In cell cultures as well as in animal models, CP-640186 can reduce tissue malonyl-CoA levels, inhibit fatty acid biosynthesis, and stimulate fatty acid oxidation. Most importantly, CP-640186 can reduce body fat mass and body weight, and improve insulin sensitivity, validating ACCs as targets for antiobesity and antidiabetes drugs.