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CAS号 | 1803605-68-6 | 货号 | BCP43518 |
中文名 | ICCB-19 HCl | ||
英文名 | ICCB-19 HCl | ||
中文别名 | |||
英文别名 | ICCB-19 hydrochloride;ICCB 19 HCl;ICCB19 HCl; | ||
SMILES | C1CCCC(CC1)NC(=O)CSC2=NCCN2.Cl | ||
化学名称 | |||
分子式 | C12H22ClN3OS | 分子量 | 291.84 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy. |
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