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CAS号 | 2173556-69-7 | 货号 | BCP32187 |
中文名 | PK68 | ||
英文名 | PK68 | ||
中文别名 | |||
英文别名 | PK-68;PK 68; | ||
SMILES | O=C(OC1CCCCC1)NC2=CC(C3=CC=C4N=C(NC(C)=O)SC4=C3)=CN=C2C | ||
化学名称 | |||
分子式 | C22H24N4O3S | 分子量 | 424.52 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PK68 is a potent and selective type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis. |
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