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| CAS号 | 2125450-76-0 | 货号 | BCP48186 |
| 中文名 | Eclitasertib | ||
| 英文名 | Eclitasertib | ||
| 中文别名 | |||
| 英文别名 | Eclitasertibum; | ||
| SMILES | CN1C(=O)C(COC2=C1N=CC=C2)NC(=O)C3=NNC(=N3)CC4=CC=CC=C4 | ||
| 化学名称 | |||
| 分子式 | C19H18N6O3 | 分子量 | 378.39 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Eclitasertib is an orally bioavailable, small-molecule inhibitor of receptor-interacting serine/threonine-protein kinase 1 (RIPK1; receptor-interacting protein 1; RIP1), with potential anti-inflammatory and immunomodulatory activities. Upon oral administration, eclitasertib disrupts RIPK1-mediated signaling, and may attenuate inflammation and the resulting tissue damage. RIPK1, a signaling protein in the tumor necrosis factor (TNF) receptor pathway, plays a key role in inflammation and cell death in response to tissue damage and pathogen recognition. | ||
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