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ABT-594 结构式

替巴克兰

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货号 :BCP19181CAS号 :198283-73-7纯度:98%
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  • 基本信息与产品描述
CAS号 198283-73-7 货号 BCP19181
关联产品 203564-54-9(Tebanicline HCl) 209326-19-2(Tebanicline dihydrochloride) 209326-18-1(Tebanicline benzoate) 198283-74-8(Tebanicline tosylate)
中文名 替巴克兰
英文名 ABT-594
中文别名
英文别名 ABT594;ABT 594;Tebanicline;Ebanicline;
SMILES
化学名称
分子式 C9H11ClN2O 分子量 198.652
纯度 98% 配送 惯例下常温包邮
产品描述 Tebanicline, also known as ABT-594 and Ebanicline, a potent synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
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